This article explores the economic and legal dimensions of multinational corporations (MNCs) operating in Cameroon and their violation of human rights. The study examines the legality of foreign investments in Cameroon, with a focus on their influence on economic growth and the negative consequences that arise from infringement of rights. More precisely, it examines the ways in which MNCs make use of Cameroon’s resources in terms of both the economy and the environment, impacting local communities. The primary objective is to understand the economic activities of MNCs in Cameroon that result in abuses of human rights. By so doing, the study provides valuable perspectives on efficiently overseeing the operations of MNCs in Cameroon. Several MNCs have a detrimental effect on Cameroonian society, resulting in both economic and environmental damage across various areas. As a result, their actions often give rise to legal conflicts, demonstrations, formal requests, and organised refusals to support their cause among the groups who are impacted. It is essential to thoroughly examine the operations of these MNCs in Cameroon, especially with the ambiguity surrounding the legality of safeguarding human rights. Based on this knowledge, it is crucial to shift the attention of foreign direct investment (FDI) in Cameroon by precisely delineating and differentiating what is beyond the scope of MNCs.